«MÉDICAMENTS D’EXCEPTION» REIMBURSEMENT CRITERIA

for moderate to severe PRURIGO NODULARIS1

These four criteria must be met for Dupixent :

20 nodules or more

Chronic pruritus for more than 6 weeks

Disease control is inadequate despite the use of topical treatment (at least one high- or very-high-potency topical corticosteroid)

The disease is insufficiently controlled after 30 or more sessions for 3 months of phototherapy (unless contraindicated, lack of accessibility or lack of effectiveness after 12 sessions for one month)

The initial application is authorized for a period of 6 months.

For the continuation of the treatment, one of these 2 criteria must be met :

Presence of 5 nosules or less

or

A reduction in the total number of lesions and a decrease of at least 4 points from baseline on the Worst Itch Numerical Rating Scale (WI-NRS) or the Peak Pruritus Numerical Rating Scale (PP-NRS)

Requests for continued treatment are allowed for up to 12 months

1 Adapted from : ANNEXE IV : LISTE DES MÉDICAMENTS D’EXCEPTION ET DES INDICATIONS RECONNUES POUR LEUR PAIEMENT (site RAMQ)